FIRST DETECTION AND ORIGIN OF MULTI-DRUG RESISTANT KLEBSIELLA PNEUMONIAE ST15 HARBORING OXA-48 IN SOUTH AMERICA

First detection and origin of multi-drug resistant Klebsiella pneumoniae ST15 harboring OXA-48 in South America

ABSTRACT: Objectives: The emergence and spread of carbapenem resistant clones is of major concern for global health.This study aimed to characterize the first detected Klebsiella pneumoniae ST15 harboring the epidemic carbapenemase OXA-48 in South America.Methods: During a routine colonization screening with carbapenem-resistant bacteria, one K.pne

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A truncated pre-F protein mRNA vaccine elicits an enhanced immune response and protection against respiratory syncytial virus

Abstract The Food and Drug Administration (FDA) has approved vaccines designed by GSK, copyright and Moderna to protect high-risk populations against respiratory syncytial virus (RSV).These vaccines employ the pre-fusion F (pre-F) protein as the immunogen.In this study, we explored an mRNA vaccine based mike and ike mini packs on a modified pre-F p

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